Astaxanthin in dogs: the evidence
What the aging-research databases and the canine literature hold for Astaxanthin (names searched: Astaxanthin). Compiled from DrugAge, the canine aging corpus and FDA CVM FOI summaries; nothing here is inferred.
Lifespan experiments in other species (DrugAge)
6 experiments recorded, by species: Caenorhabditis elegans 4, Mus musculus 2.
NIA Interventions Testing Program rows
| Species | Strain | Dose | Age at start | Duration | Sex | Mean lifespan Δ% | Mean sig. | Max lifespan Δ% | Max sig. | Source |
|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | UM-HET3 | 4000 ppm food | 12 months | until death | Female | 3 | NS | -1 | NS | PMID 38041783 |
| Mus musculus | UM-HET3 | 4000 ppm food | 12 months | until death | Male | 12 | S | 6 | NS | PMID 38041783 |
Other DrugAge rows (sample)
| Species | Strain | Dose | Age at start | Duration | Sex | Mean lifespan Δ% | Mean sig. | Max lifespan Δ% | Max sig. | Source |
|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | N2 | 1 mM | Unknown | 28.6 | S | 21.7 | NA | PMID 22013497 | ||
| Caenorhabditis elegans | N2 | 6 µg | Unknown | 20.8 | S | 14.6 | NA | PMID 22484623 | ||
| Caenorhabditis elegans | N2 | 120 µM | Unknown | 13.36 | S | NA | PMID 33115330 | |||
| Caenorhabditis elegans | N2 | 60 µM | Unknown | 9.71 | S | NA | PMID 33115330 |
Lifespan experiments in dogs (DrugAge)
DrugAge records no dog lifespan experiment for this compound.
Dog-equivalent doses (allometric starting points, not recommendations)
Method: FDA 2005 Km body-surface-area conversion; starting-point heuristic only.
No mg/kg dose in DrugAge to translate (doses reported as ppm of diet or a concentration).
Canine aging literature (Europe PMC corpus)
6 corpus records mention this compound.
Top hits in the core tier
- METHODS AND COMPOSITIONS UTILIZING ASTAXANTHIN. (, 2005).
- METHODS AND COMPOSITIONS UTILIZING ASTAXANTHIN (, 2005).
- METHODS AND COMPOSITIONS UTILIZING ASTAXANTHIN (, 2004).
- Methods and compositions utilizing astaxanthin (, 2004).
- Astaxanthin modulates age-associated mitochondrial dysfunction in healthy dogs. (Journal of animal science, 2013). PMID 23100599
- A protein- and fiber-rich diet with astaxanthin alleviates high-fat diet-induced obesity in beagles. (Frontiers in nutrition, 2022). PMID 36352906
FDA CVM FOI summaries for dog products
No FDA FOI summary for a dog product contains this ingredient (it is not a marketed veterinary product).
Evidence gaps reported by the dossier tool
- DrugAge has no dog lifespan experiment for this compound.
- Corpus mentions exist but no randomized/placebo-controlled dog trial surfaced for it.
- No mg/kg animal dose in DrugAge to translate (doses reported as ppm or % of diet).
- No FDA FOI summary for a dog product containing this ingredient.
Reproduce: intervention_dossier(compound="Astaxanthin") in dog-geroscience-mcp.