SG1002 (hydrogen sulfide donor) in dogs: the evidence

What the aging-research databases and the canine literature hold for SG1002 (hydrogen sulfide donor) (names searched: SG1002 (hydrogen sulfide donor), SG1002-(hydrogen-sulfide-donor)). Compiled from DrugAge, the canine aging corpus and FDA CVM FOI summaries; nothing here is inferred.

Lifespan experiments in other species (DrugAge)

4 experiments recorded, by species: Mus musculus 4.

NIA Interventions Testing Program rows

Species	Strain	Dose	Age at start	Duration	Sex	Mean lifespan Δ%	Mean sig.	Max lifespan Δ%	Max sig.	Source
Mus musculus	UM-HET3	240 ppm food	5-9 months	until death	Female	-2	NS	-2	NS	PMID 38041783
Mus musculus	UM-HET3	240 ppm food	5-9 months	until death	Male	0	NS	3	NS	PMID 38041783
Mus musculus	UM-HET3	240 ppm food	16 months	until death	Female	1	NS	4	NS	PMID 38041783
Mus musculus	UM-HET3	240 ppm food	16 months	until death	Male	2	NS	1	NS	PMID 38041783

Lifespan experiments in dogs (DrugAge)

DrugAge records no dog lifespan experiment for this compound.

Dog-equivalent doses (allometric starting points, not recommendations)

Method: FDA 2005 Km body-surface-area conversion; starting-point heuristic only.

No mg/kg dose in DrugAge to translate (doses reported as ppm of diet or a concentration).

Canine aging literature (Europe PMC corpus)

0 corpus records mention this compound.

FDA CVM FOI summaries for dog products

No FDA FOI summary for a dog product contains this ingredient (it is not a marketed veterinary product).

Evidence gaps reported by the dossier tool

DrugAge has no dog lifespan experiment for this compound.
No record in the canine aging corpus mentions this compound.
No mg/kg animal dose in DrugAge to translate (doses reported as ppm or % of diet).
No FDA FOI summary for a dog product containing this ingredient.

Reproduce: intervention_dossier(compound="SG1002 (hydrogen sulfide donor)") in dog-geroscience-mcp.