Protandim in dogs: the evidence

What the aging-research databases and the canine literature hold for Protandim (names searched: Protandim). Compiled from DrugAge, the canine aging corpus and FDA CVM FOI summaries; nothing here is inferred.

Lifespan experiments in other species (DrugAge)

2 experiments recorded, by species: Mus musculus 2.

NIA Interventions Testing Program rows

SpeciesStrainDoseAge at startDurationSexMean lifespan Δ%Mean sig.Max lifespan Δ%Max sig.Source
Mus musculusUM-HET3600 ppm food 10-17 months, 1200 ppm food (17 months-death)10 monthsuntil deathFemale3S6NSPMID 27312235
Mus musculusUM-HET3600 ppm food 10-17 months, 1200 ppm food (17 months-death)10 monthsuntil deathMale7S6NSPMID 27312235

Lifespan experiments in dogs (DrugAge)

DrugAge records no dog lifespan experiment for this compound.

Dog-equivalent doses (allometric starting points, not recommendations)

Method: FDA 2005 Km body-surface-area conversion; starting-point heuristic only.

No mg/kg dose in DrugAge to translate (doses reported as ppm of diet or a concentration).

Canine aging literature (Europe PMC corpus)

0 corpus records mention this compound.

FDA CVM FOI summaries for dog products

No FDA FOI summary for a dog product contains this ingredient (it is not a marketed veterinary product).

Evidence gaps reported by the dossier tool

Reproduce: intervention_dossier(compound="Protandim") in dog-geroscience-mcp.