Green tea extract in dogs: the evidence
What the aging-research databases and the canine literature hold for Green tea extract (names searched: Green tea extract, Green-tea-extract). Compiled from DrugAge, the canine aging corpus and FDA CVM FOI summaries; nothing here is inferred.
Lifespan experiments in other species (DrugAge)
14 experiments recorded, by species: Drosophila melanogaster 9, Mus musculus 3, Caenorhabditis elegans 2.
NIA Interventions Testing Program rows
| Species | Strain | Dose | Age at start | Duration | Sex | Mean lifespan Δ% | Mean sig. | Max lifespan Δ% | Max sig. | Source |
|---|---|---|---|---|---|---|---|---|---|---|
| Mus musculus | UM-HET3 | 2000 ppm food | 4 months | until death | Female | 7 | NS | 0 | NS | PMID 22451473 |
| Mus musculus | UM-HET3 | 2000 ppm food | 4 months | until death | Male | 5 | NS | 0 | NS | PMID 22451473 |
Other DrugAge rows (sample)
| Species | Strain | Dose | Age at start | Duration | Sex | Mean lifespan Δ% | Mean sig. | Max lifespan Δ% | Max sig. | Source |
|---|---|---|---|---|---|---|---|---|---|---|
| Caenorhabditis elegans | 0.25 mg/ml | Unknown | S | NA | PMID 28750751 | |||||
| Caenorhabditis elegans | 0.125 mg/ml | Unknown | S | NA | PMID 28750751 | |||||
| Drosophila melanogaster | Oregon R | Instead of water | Male | 15.7 | S | NA | PMID 8326745 | |||
| Drosophila melanogaster | Oregon R | 1:10 dilution | Male | 7 | S | NA | PMID 8326745 | |||
| Drosophila melanogaster | Oregon R | Instead of water | Male | 20.2 | S | NA | PMID 8326745 | |||
| Drosophila melanogaster | Oregon R | Instead of water | Male | 12.2 | S | NA | PMID 8326745 | |||
| Drosophila melanogaster | Oregon R | Instead of water | Male | 8.6 | S | NA | PMID 8326745 | |||
| Drosophila melanogaster | Oregon-R-C | 1 mg/ml | Unknown | 5.9 | S | 5.3 | NA | PMID 17440995 | ||
| Drosophila melanogaster | Oregon-R-C | 10 mg/ml | Unknown | 15.7 | S | 5.3 | NA | PMID 17440995 | ||
| Drosophila melanogaster | Oregon-R-C | 5 mg/ml | Unknown | 7.8 | S | 5.3 | NA | PMID 17440995 | ||
| Drosophila melanogaster | w1118 | 10 mg/ml | Male | 19 | S | NA | PMID 25058464 | |||
| Mus musculus | C57BL/6JHsd | 80 ppm water | 13 months | until death | Male | 6 | S | 1 | NS | PMID 17516143 |
Lifespan experiments in dogs (DrugAge)
DrugAge records no dog lifespan experiment for this compound.
Dog-equivalent doses (allometric starting points, not recommendations)
Method: FDA 2005 Km body-surface-area conversion; starting-point heuristic only.
No mg/kg dose in DrugAge to translate (doses reported as ppm of diet or a concentration).
Canine aging literature (Europe PMC corpus)
1 corpus records mention this compound.
Top hits in the core tier
- Green Tea Extract, Keratin Hydrolysate and Vitamin C Exert Anti-Ageing Effects Through the Hippo Signalling Pathway in Feline and Canine Mammary Gland Cells. (Veterinary medicine and science, 2026). PMID 42499304
FDA CVM FOI summaries for dog products
No FDA FOI summary for a dog product contains this ingredient (it is not a marketed veterinary product).
Evidence gaps reported by the dossier tool
- DrugAge has no dog lifespan experiment for this compound.
- Corpus mentions exist but no randomized/placebo-controlled dog trial surfaced for it.
- No mg/kg animal dose in DrugAge to translate (doses reported as ppm or % of diet).
- No FDA FOI summary for a dog product containing this ingredient.
Reproduce: intervention_dossier(compound="Green tea extract") in dog-geroscience-mcp.